Mexico signed the Stockholm Convention on 23 May 2001 and ratified it on 10 February 2003, becoming the first Latin American nation to ratify the Stockholm Convention. Environmentally sound management of PCBs and their safe phase-out are national priorities as outlined in Mexico’s National Implementation Plan (NIP) for the Stockholm Convention, which was submitted on 12 February 2008. The Federal Ministry of Environment of Mexico (SEMARNAT), with support from GEF and UNDP, is working towards eliminating the threat from PCBs to human health by instituting a necessary legal framework, building capacity, raising awareness and piloting innovative schemes to cost-effectively manage and destroy PCBs. These efforts aim to implement activities to ensure Mexico’s compliance with Stockholm Convention requirements for PCB management and destruction through the follow-up to the NIP, thereby minimizing risks of exposure from PCBs to Mexicans, including vulnerable populations, and to the environment.