The Papua New Guinea Preparedness and Response Plan is a national plan with a multi-sectoral approach. This Plan aims at minimizing the health and socio-economic impacts of Covid-19 on the public by strengthening the core capacities for health security, preventing or delaying the entry of the virus, preventing local transmission by timely detection, rapid response and ensuring public trust and community participation. This Plan lays down measures according to 4 phases with possible scenarios to cope with Covid-19 outbreak to mitigate health, social and economic impacts on people s health and well-being. This Plan focuses on 10 priority areas which are identified as (I) incident management and planning; (II) surveillance, risk assessment and rapid response; (III) laboratory; (IV) clinical management and health care services; (V) infection prevention and control; (VI) non-pharmaceutical public health measures; (VII) risk communication and community engagement; (VIII) points of entry; (IX) operational logistics; and (X) partner coordination.